Rotavirus Replication: Plus-Sense Templates for Double-Stranded RNA Synthesis Are Made in Viroplasms

Rotavirus plus-strand RNAs not only direct protein synthesis but also serve as templates for the synthesis of the segmented double-stranded RNA (dsRNA) genome. In this study, we identified short-interfering RNAs (siRNAs) for viral genes 5, 8, and 9 that suppressed the expression of NSP1, a nonessent...

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Bibliographic Details
Main Authors: Silvestri, Lynn S., Taraporewala, Zenobia F., Patton, John T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC434085/
https://ncbi.nlm.nih.gov/pubmed/15220450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.14.7763-7774.2004
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