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Human Coronavirus 229E Nonstructural Protein 13: Characterization of Duplex-Unwinding, Nucleoside Triphosphatase, and RNA 5′-Triphosphatase Activities
The human coronavirus 229E (HCoV-229E) replicase gene-encoded nonstructural protein 13 (nsp13) contains an N-terminal zinc-binding domain and a C-terminal superfamily 1 helicase domain. A histidine-tagged form of nsp13, which was expressed in insect cells and purified, is reported to unwind efficien...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2004
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC434081/ https://ncbi.nlm.nih.gov/pubmed/15220459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.14.7833-7838.2004 |
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