Human Coronavirus 229E Nonstructural Protein 13: Characterization of Duplex-Unwinding, Nucleoside Triphosphatase, and RNA 5′-Triphosphatase Activities

The human coronavirus 229E (HCoV-229E) replicase gene-encoded nonstructural protein 13 (nsp13) contains an N-terminal zinc-binding domain and a C-terminal superfamily 1 helicase domain. A histidine-tagged form of nsp13, which was expressed in insect cells and purified, is reported to unwind efficien...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Ivanov, Konstantin A., Ziebuhr, John
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434081/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15220459/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.14.7833-7838.2004
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