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BIPOLAR DISORDER AND SUBSTANCE ABUSE: PATHOLOGICAL AND THERAPEUTIC IMPLICATIONS OF THEIR COMORBIDITY AND CROSS SENSITIZATION

BACKGROUND: Bipolar disorder has a high co-occurrence with substance abuse disorders, but the pathophysiological mechanisms have not been adequately explored. AIMS: Review the role of stress in the onset and recurrence of affective episodes and substance abuse. METHOD: We review the mechanisms invol...

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Detalhes bibliográficos
Publicado no:Br J Psychiatry
Main Authors: Post, Robert M., Kalivas, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340700/
https://ncbi.nlm.nih.gov/pubmed/23457180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1192/bjp.bp.112.116855
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