Neutrophil-derived JAML Inhibits Repair of Intestinal Epithelial Injury During Acute Inflammation

Neutrophil transepithelial migration (TEM) during acute inflammation is associated with mucosal injury. Using models of acute mucosal injury in-vitro and in-vivo, we describe a new mechanism by which neutrophils infiltrating the intestinal mucosa disrupt epithelial homeostasis. We report that juncti...

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Détails bibliographiques
Publié dans:Mucosal Immunol
Auteurs principaux: Weber, Dominique A., Sumagin, Ronen, McCall, Ingrid C., Leoni, Giovanna, Neumann, Philipp A., Andargachew, Rakieb, Brazil, Jennifer C., Medina-Contreras, Oscar, Denning, Timothy L., Nusrat, Asma, Parkos, Charles A.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340686/
https://ncbi.nlm.nih.gov/pubmed/24621992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.12
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