Comparison of a PfHRP2-based rapid diagnostic test and PCR for malaria in a low prevalence setting in rural southern Zambia: implications for elimination

BACKGROUND: Rapid diagnostic tests (RDTs) detecting histidine-rich protein 2 (PfHRP2) antigen are used to identify individuals with Plasmodium falciparum infection even in low transmission settings seeking to achieve elimination. However, these RDTs lack sensitivity to detect low-density infections,...

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Publicat a:Malar J
Autors principals: Laban, Natasha M, Kobayashi, Tamaki, Hamapumbu, Harry, Sullivan, David, Mharakurwa, Sungano, Thuma, Philip E, Shiff, Clive J, Moss, William J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340619/
https://ncbi.nlm.nih.gov/pubmed/25888818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0544-3
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