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A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex
Most transmembrane proteins are selected as transport vesicle cargo through the recognition of short, linear amino acid motifs in their cytoplasmic portions by vesicle coat proteins. In the case of clathrin-coated vesicles (CCVs) the motifs are recognised by clathrin adaptors. The AP2 adaptor comple...
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| Veröffentlicht in: | Nature |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4340503/ https://ncbi.nlm.nih.gov/pubmed/19140243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07422 |
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