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Exposure to CYP3A4 inducing and CYP3A4 non-inducing antiepileptic agents and the risk of fractures

PURPOSE: To evaluate whether exposure to CYP3A4 inducing antiepileptics increases fracture risk compared to CYP3A4 non-inducing antiepileptics. METHODS: We performed a retrospective cohort study of initiators of antiepileptic agents using a UK medical record database (The Health Improvement Network)...

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Publicat a:Pharmacoepidemiol Drug Saf
Autors principals: Schelleman, Hedi, Pollard, John R., Newcomb, Craig, Markowitz, Clyde E., Bilker, Warren B., Leonard, Mary B., Hennessy, Sean
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340253/
https://ncbi.nlm.nih.gov/pubmed/21538673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pds.2141
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