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Involvement of sigma-1 receptor in astrocyte activation induced by methamphetamine via up-regulation of its own expression

BACKGROUND: Although it has been documented that methamphetamine induces astrocyte activation, the mechanism(s) underlying this effect remain poorly understood. We thus sought to examine the molecular mechanisms involved in methamphetamine-mediated activation of astrocytes with a focus on the role o...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Zhang, Yuan, Lv, Xuan, Bai, Ying, Zhu, Xinjian, Wu, Xiaodong, Chao, Jie, Duan, Ming, Buch, Shilpa, Chen, Ling, Yao, Honghong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340104/
https://ncbi.nlm.nih.gov/pubmed/25889537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0250-7
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