Aryl hydrocarbon receptor-induced adrenomedullin mediates cigarette smoke carcinogenicity in humans and mice

Cigarette smoke (CS) is a leading cause of death worldwide. The aryl hydrocarbon receptor (AHR) is partially responsible for tobacco-induced carcinogenesis although the underlying mechanisms involving early effector genes have yet to be determined. Here, we report that adrenomedullin (ADM) significa...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Portal-Nuñez, Sergio, Shankavaram, Uma, Rao, Mahadev, Datrice, Nicole, Scott, Atay, Aparicio, Marta, Camphausen, Kevin A., Fernández-Salguero, Pedro M., Chang, Han, Lin, Pinpin, Schrump, David S., Garantziotis, Stavros, Cuttitta, Frank, Zudaire, Enrique
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340077/
https://ncbi.nlm.nih.gov/pubmed/22993405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0818
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