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Reverse Transcriptase: Correlation of Zinc Content with Activity

Evidence is presented that DNA polymerase of avian myeloblastosis virus has an obligatory zinc requirement for activity. Previous studies indicate that the purified polymerase contains zinc in a stoichiometry of about 1 g-atom/mole. We now find that the enzyme-bound zinc is exchangeable with radioac...

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Detalhes bibliográficos
Main Authors: Poiesz, Bernard J., Seal, Gita, Loeb, Lawrence A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC434005/
https://ncbi.nlm.nih.gov/pubmed/4140513
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