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Biosynthesis of Collagen Crosslinks: Increased Activity of Purified Lysyl Oxidase with Reconstituted Collagen Fibrils

Lysyl oxidase catalyzes the formation of crosslinking aldehydes in collagen and elastin. This report demonstrates that the enzyme has high activity with collagen precipitated as native fibrils, an apparent K(m) of 0.95 μM, and low activity toward either soluble forms such as denatured collagen, isol...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Author: Siegel, Robert C.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1974
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433990/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4531019/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.12.4826
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