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Biosynthesis of Collagen Crosslinks: Increased Activity of Purified Lysyl Oxidase with Reconstituted Collagen Fibrils

Lysyl oxidase catalyzes the formation of crosslinking aldehydes in collagen and elastin. This report demonstrates that the enzyme has high activity with collagen precipitated as native fibrils, an apparent K(m) of 0.95 μM, and low activity toward either soluble forms such as denatured collagen, isol...

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Pubblicato in:Proc Natl Acad Sci U S A
Autore principale: Siegel, Robert C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1974
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433990/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4531019/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.12.4826
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