Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicity

To cause food-borne botulism, botulinum neurotoxin (BoNT) in the gastrointestinal lumen must traverse the intestinal epithelial barrier. However, the mechanism by which BoNT crosses the intestinal epithelial barrier remains unclear. BoNTs are produced along with one or more non-toxic components, wit...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Matsumura, Takuhiro, Sugawara, Yo, Yutani, Masahiro, Amatsu, Sho, Yagita, Hideo, Kohda, Tomoko, Fukuoka, Shin-Ichi, Nakamura, Yutaka, Fukuda, Shinji, Hase, Koji, Ohno, Hiroshi, Fujinaga, Yukako
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Pub. Group 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339894/
https://ncbi.nlm.nih.gov/pubmed/25687350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7255
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