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On the Mechanism of Pyridoxine Responsive Homocystinuria. II. Properties of Normal and Mutant Cystathionine β-Synthase from Cultured Fibroblasts

Cystathionine β-synthase [L-serine hydrolyase (adding homocysteine), EC 4.2.1.22] was studied in cultured skin fibroblasts from two control subjects and three patients with pyridoxine-responsive homocystinuria. In crude cell sonicates, cystathionine synthase activity detected in each mutant line was...

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Detalhes bibliográficos
Main Authors: Kim, Young Jin, Rosenberg, Leon E.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC433989/
https://ncbi.nlm.nih.gov/pubmed/4531018
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