A systematic evaluation of high-dimensional, ensemble-based regression for exploring large model spaces in microbiome analyses

BACKGROUND: Microbiome studies incorporate next-generation sequencing to obtain profiles of microbial communities. Data generated from these experiments are high-dimensional with a rich correlation structure but modest sample sizes. A statistical model that utilizes these microbiome profiles to expl...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Shankar, Jyoti, Szpakowski, Sebastian, Solis, Norma V, Mounaud, Stephanie, Liu, Hong, Losada, Liliana, Nierman, William C, Filler, Scott G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339743/
https://ncbi.nlm.nih.gov/pubmed/25638274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0467-6
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