The Phosphoinositide 3-Kinase Signaling Pathway is Involved in the Control of Modified Low-Density Lipoprotein Uptake by Human Macrophages

The transformation of macrophages into lipid-loaded foam cells is a critical early event in the pathogenesis of atherosclerosis. Both receptor-mediated uptake of modified LDL, mediated primarily by scavenger receptors-A (SR-A) and CD36 along with other proteins such as lipoprotein lipase (LPL), and...

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Detalhes bibliográficos
Publicado no:Lipids
Main Authors: Michael, Daryn R., Davies, Thomas S., Laubertová, Lucia, Gallagher, Hayley, Ramji, Dipak P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339697/
https://ncbi.nlm.nih.gov/pubmed/25663263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11745-015-3993-0
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