Effect of Alkylureas on the Polymerization of Hemoglobin S
Alkylureas (methyl-, ethyl-, propyl-, and butyl-) can inhibit both the gelation of deoxyhemoglobin S and red cell sickling without denaturation of the hemoglobin or intrinsic alteration of its oxygen affinity. This effect is directly proportional to the length of the alkyl chain and substantiates th...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1974
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433967/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4531011/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.12.4718 |
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