Prevalence of Germline Mutations in Cancer Predisposition Genes in Patients with Pancreatic Cancer

BACKGROUND & AIMS: We investigated the prevalence of germline mutations in APC, ATM, BRCA1, BRCA2, CDKN2A, MLH1, MSH2, MSH6, PALB2, PMS2, PRSS1, STK11, and TP53 in patients with pancreatic cancer. METHODS: The Ontario Pancreas Cancer Study enrolls consenting participants with pancreatic cancer f...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Grant, Robert C., Selander, Iris, Connor, Ashton A., Selvarajah, Shamini, Borgida, Ayelet, Briollais, Laurent, Petersen, Gloria M., Lerner-Ellis, Jordan, Holter, Spring, Gallinger, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339623/
https://ncbi.nlm.nih.gov/pubmed/25479140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.11.042
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