Polymorphism in the corticotropin-releasing factor receptor 1 (CRF1-R) gene plays a role in shaping the high anxious phenotype of Marchigian Sardinian alcohol-preferring (msP) rats

Marchigian-Sardinian alcohol-preferring (msP) rats exhibit innate preference for alcohol along with anxious phenotype. In these animals, two single nucleotide polymorphisms in position −1836 and −2097 from the first start codon of the CRF1-R transcript have been found. Here we examined whether these...

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Udgivet i:Psychopharmacology (Berl)
Main Authors: Cippitelli, Andrea, Ayanwuyi, Lydia O., Barbier, Estelle, Domi, Esi, Lerma-Cabrera, Jose M., Carvajal, Francisca, Scuppa, Giulia, Li, Hongwu, Ubaldi, Massimo, Heilig, Markus, Roberto, Marisa, Ciccocioppo, Roberto
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339612/
https://ncbi.nlm.nih.gov/pubmed/25260340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3743-7
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