Motor neuron cell bodies are actively positioned by Slit/Robo repulsion and Netrin/DCC attraction

Motor neurons differentiate from a ventral column of progenitors and settle in static clusters, the motor nuclei, next to the floor plate. Within these cell clusters, motor neurons receive afferent input and project their axons out to muscle targets. The molecular mechanisms that position motor neur...

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Bibliographic Details
Published in:Dev Biol
Main Authors: Kim, Minkyung, Fontelonga, Tatiana, Roesener, Andrew P, Lee, Haeram, Gurung, Suman, Mendonca, Philipe RF, Mastick, Grant S
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339514/
https://ncbi.nlm.nih.gov/pubmed/25530182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.12.014
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