Levels of PAH-DNA Adducts in Cord Blood and Cord Tissue and the Risk of Fetal Neural Tube Defects in a Chinese Population

INTRODUCTION: Maternal exposure to polycyclic aromatic hydrocarbons (PAHs) has been shown to be associated with an elevated risk for neural tube defects (NTDs). In the human body, PAHs are bioactivated and the resultant reactive epoxides can covalently bind to DNA to form PAH-DNA adducts, which may,...

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Udgivet i:Neurotoxicology
Main Authors: Yi, Deqing, Yuan, Yue, Jin, Lei, Zhou, Guodong, Zhu, Huiping, Finnell, Richard H., Ren, Aiguo
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339482/
https://ncbi.nlm.nih.gov/pubmed/25522656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2014.12.003
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