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Muscarinic excitation of parvalbumin-positive interneurons contributes to the severity of pilocarpine-induced seizures
OBJECTIVE: A common rodent model in epilepsy research employs the muscarinic acetylcholine receptor (mAChR) agonist pilocarpine, yet the mechanisms underlying the induction of pilocarpine-induced seizures (PISs) remain unclear. Global M(1) mAChR (M(1)R) knockout mice are resistant to PISs, implying...
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| Publicado no: | Epilepsia |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4339470/ https://ncbi.nlm.nih.gov/pubmed/25495999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12883 |
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