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Probing protein disorder and complexity at single-molecule resolution

A substantial fraction of the human proteome encodes disordered proteins. Protein disorder is associated with a variety of cellular functions and misfunction, and is therefore of clear import to biological systems. However, disorder lends itself to conformational flexibility and heterogeneity, rende...

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Detalhes bibliográficos
Publicado no:Semin Cell Dev Biol
Main Authors: Lee, Taehyung, Moran-Gutierrez, Crystal R., Deniz, Ashok A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339442/
https://ncbi.nlm.nih.gov/pubmed/25305580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2014.09.027
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