Posttranslational Modification of Sirt6 Activity by Peroxynitrite

The mammalian sirtuin 6 (Sirt6) is a site-specific histone deacetylase that regulates chromatin structure and many fundamental biological processes. It inhibits endothelial cell senescence and inflammation, prevents development of cardiac hypertrophy and heart failure, modulates glucose metabolism,...

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Bibliografiske detaljer
Udgivet i:Free Radic Biol Med
Main Authors: Hu, Shuqun, Liu, Hua, Ha, Yonju, Luo, Xuemei, Motamedi, Massoud, Gupta, Mahesh P., Ma, Jian-Xing, Tilton, Ronald G., Zhang, Wenbo
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339438/
https://ncbi.nlm.nih.gov/pubmed/25476852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.11.011
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