Active Immunization with an Octa-Valent Staphylococcus aureus Antigen Mixture in Models of S. aureus Bacteremia and Skin Infection in Mice

Proteomic studies with different Staphylococcus aureus isolates have shown that the cell surface-exposed and secreted proteins IsaA, LytM, Nuc, the propeptide of Atl (pro-Atl) and four phenol-soluble modulins α (PSMα) are invariantly produced by this pathogen. Therefore the present study was aimed a...

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Udgivet i:PLoS One
Main Authors: van den Berg, Sanne, Koedijk, Dennis G. A. M., Back, Jaap Willem, Neef, Jolanda, Dreisbach, Annette, van Dijl, Jan Maarten, Bakker-Woudenberg, Irma A. J. M., Buist, Girbe
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339199/
https://ncbi.nlm.nih.gov/pubmed/25710376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116847
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