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Glucose Inhibition of Epinephrine Stimulation of Hepatic Gluconeogenesis by Blockade of the α-Receptor Function

For isolated rat hepatocytes, glucagon, 3′:5′-cyclic AMP, 3′:5′-cyclic GMP, and epinephrine stimulate the rate of gluconeogenesis from substrates not involving pathways of mitochondrial metabolism. From estimation of the rates of glucose formation, fructose 6-phosphate phosphorylation, and lactate a...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kneer, Nancy M., Bosch, Anne L., Clark, Michael G., Lardy, Henry A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1974
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Biological Sciences: Biochemistry
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433919/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4155070/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.11.4523
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