TNF-alpha Produced in the Kidney Contributes to Angiotensin II-dependent Hypertension

Immune system activation contributes to the pathogenesis of hypertension and the resulting progression of chronic kidney disease (CKD). In this regard, we recently identified a role for pro-inflammatory Th1 T lymphocyte responses in hypertensive kidney injury. As Th1 cells generate IFN-γ and TNF-α,...

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Bibliographic Details
Published in:Hypertension
Main Authors: Zhang, Jiandong, Patel, Mehul B., Griffiths, Robert, Mao, Alice, Song, Young-soo, Karlovich, Norah S., Sparks, Matthew A., Jin, Huixia, Wu, Min, Lin, Eugene E., Crowley, Steven D.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339088/
https://ncbi.nlm.nih.gov/pubmed/25185128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03863
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