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Biological Membranes as Bilayer Couples. A Molecular Mechanism of Drug-Erythrocyte Interactions

We propose that membranes whose proteins and polar lipids are distributed asymmetrically in the two halves of the membrane bilayer can act as bilayer couples, i.e., the two halves can respond differently to a perturbation. This hypothesis is applied to the interactions of amphipathic drugs with huma...

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Detalhes bibliográficos
Main Authors: Sheetz, Michael P., Singer, S. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC433905/
https://ncbi.nlm.nih.gov/pubmed/4530994
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