HER2 activation results in β-catenin-dependent changes in pulmonary epithelial permeability

The receptor tyrosine kinase human epidermal growth factor receptor-2 (HER2) is known to regulate pulmonary epithelial barrier function; however, the mechanisms behind this effect remain unidentified. We hypothesized that HER2 signaling alters the epithelial barrier through an interaction with the a...

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Bibliographic Details
Published in:Am J Physiol Lung Cell Mol Physiol
Main Authors: Finigan, James H., Vasu, Vihas T., Thaikoottathil, Jyoti V., Mishra, Rangnath, Shatat, Mohammad A., Mason, Robert J., Kern, Jeffrey A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2014
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338945/
https://ncbi.nlm.nih.gov/pubmed/25326580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00237.2014
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