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Kaposi's Sarcoma-Associated Herpesvirus Induces Nrf2 Activation in Latently Infected Endothelial Cells through SQSTM1 Phosphorylation and Interaction with Polyubiquitinated Keap1

Nuclear factor erythroid 2-related factor 2 (Nrf2), the cellular master regulator of the antioxidant response, dissociates from its inhibitor Keap1 when activated by stress signals and participates in the pathogenesis of viral infections and tumorigenesis. Early during de novo infection of endotheli...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Gjyshi, Olsi, Flaherty, Stephanie, Veettil, Mohanan Valiya, Johnson, Karen E., Chandran, Bala, Bottero, Virginie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338888/
https://ncbi.nlm.nih.gov/pubmed/25505069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02742-14
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