Lethal Coinfection of Influenza Virus and Streptococcus pneumoniae Lowers Antibody Response to Influenza Virus in Lung and Reduces Numbers of Germinal Center B Cells, T Follicular Helper Cells, and Plasma Cells in Mediastinal Lymph Node

Secondary Streptococcus pneumoniae infection after influenza is a significant clinical complication resulting in morbidity and sometimes mortality. Prior influenza virus infection has been demonstrated to impair the macrophage and neutrophil response to the subsequent pneumococcal infection. In cont...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wu, Yuet, Tu, Wenwei, Lam, Kwok-Tai, Chow, Kin-Hung, Ho, Pak-Leung, Guan, Yi, Peiris, Joseph S. Malik, Lau, Yu-Lung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338877/
https://ncbi.nlm.nih.gov/pubmed/25428873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02455-14
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