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HDAC4 as a potential therapeutic target in neurodegenerative diseases: a summary of recent achievements

For the past decade protein acetylation has been shown to be a crucial post-transcriptional modification involved in the regulation of protein functions. Histone acetyltransferases (HATs) mediate acetylation of histones which results in the nucleosomal relaxation associated with gene expression. The...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Mielcarek, Michal, Zielonka, Daniel, Carnemolla, Alisia, Marcinkowski, Jerzy T., Guidez, Fabien
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338808/
https://ncbi.nlm.nih.gov/pubmed/25759639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00042
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