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Computational analysis of the LRRK2 interactome

LRRK2 was identified in 2004 as the causative protein product of the Parkinson’s disease locus designated PARK8. In the decade since then, genetic studies have revealed at least 6 dominant mutations in LRRK2 linked to Parkinson’s disease, alongside one associated with cancer. It is now well establis...

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Bibliografske podrobnosti
izdano v:PeerJ
Main Authors: Manzoni, Claudia, Denny, Paul, Lovering, Ruth C., Lewis, Patrick A.
Format: Artigo
Jezik:Inglês
Izdano: PeerJ Inc. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338795/
https://ncbi.nlm.nih.gov/pubmed/25737818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.778
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