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Regulation of Herpesvirus Macromolecular Synthesis: Nuclear Retention of Nontranslated Viral RNA Sequences

We report two instances of selective accumulation of herpes simplex 1 RNA transcripts in different compartments of infected HEp-2 cells. In the first, transcripts derived from about 50% of the viral DNA accumulated in the nuclei of cells 8 hr after infection. However, only 40-42% of the DNA was repr...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kozak, M., Roizman, B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1974
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433874/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4373710/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.11.4322
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