Anti‐Inflammatory Immune Skewing Is Atheroprotective: Apoe(−/−)FcγRIIb(−/−) Mice Develop Fibrous Carotid Plaques

BACKGROUND: Stroke, caused by carotid plaque rupture, is a major cause of death in the United States. Whereas vulnerable human plaques have higher Fc receptor (FcγR) expression than their stable counterparts, how FcγR expression impacts plaque histology is unknown. We investigated the role of FcγRII...

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Veröffentlicht in:J Am Heart Assoc
Hauptverfasser: Harmon, Erin Y., Fronhofer, Van, Keller, Rebecca S., Feustel, Paul J., Zhu, Xinmei, Xu, Hao, Avram, Dorina, Jones, David M., Nagarajan, Shanmugam, Lennartz, Michelle R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2014
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338708/
https://ncbi.nlm.nih.gov/pubmed/25516435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001232
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