Anti‐Inflammatory Immune Skewing Is Atheroprotective: Apoe(−/−)FcγRIIb(−/−) Mice Develop Fibrous Carotid Plaques

BACKGROUND: Stroke, caused by carotid plaque rupture, is a major cause of death in the United States. Whereas vulnerable human plaques have higher Fc receptor (FcγR) expression than their stable counterparts, how FcγR expression impacts plaque histology is unknown. We investigated the role of FcγRII...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Harmon, Erin Y., Fronhofer, Van, Keller, Rebecca S., Feustel, Paul J., Zhu, Xinmei, Xu, Hao, Avram, Dorina, Jones, David M., Nagarajan, Shanmugam, Lennartz, Michelle R.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338708/
https://ncbi.nlm.nih.gov/pubmed/25516435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001232
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