Tenascin‐C Aggravates Autoimmune Myocarditis via Dendritic Cell Activation and Th17 Cell Differentiation

BACKGROUND: Tenascin‐C (TN‐C), an extracellular matrix glycoprotein, appears at several important steps of cardiac development in the embryo, but is sparse in the normal adult heart. TN‐C re‐expresses under pathological conditions including myocarditis, and is closely associated with tissue injury a...

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Detalles Bibliográficos
Publicado en:J Am Heart Assoc
Main Authors: Machino‐Ohtsuka, Tomoko, Tajiri, Kazuko, Kimura, Taizo, Sakai, Satoshi, Sato, Akira, Yoshida, Toshimichi, Hiroe, Michiaki, Yasutomi, Yasuhiro, Aonuma, Kazutaka, Imanaka‐Yoshida, Kyoko
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2014
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338691/
https://ncbi.nlm.nih.gov/pubmed/25376187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001052
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