The Three-Dimensional Structure of a Phosphorylcholine-Binding Mouse Immunoglobulin Fab and the Nature of the Antigen Binding Site

The structure of the Fab of McPC 603, a mouse myeloma protein with phosphorylcholine binding activity, has been determined to 3.1-Å resoltuion. The four domains are found to be structurally similar with a well-defined double-layer structure. A large cavity exists at one end of the fragment, the wall...

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Argitaratua izan da:	Proc Natl Acad Sci U S A
Egile Nagusiak:	Segal, David M., Padlan, Eduardo A., Cohen, Gerson H., Rudikoff, Stuart, Potter, Michael, Davies, David R.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	National Academy of Sciences 1974
Gaiak:	Biological Sciences: Immunology
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433869/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4530984/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.11.4298
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