Role and species–specific expression of colon T cell homing receptor GPR15 in colitis

Lymphocyte recruitment maintains intestinal immune homeostasis but also contributes to inflammation. The orphan chemoattractant receptor GPR15 mediates regulatory T cell homing and immunosuppression in the mouse colon. We show that GPR15 is also expressed by mouse T(H)17 and T(H)1 effector cells, an...

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Veröffentlicht in:Nat Immunol
Hauptverfasser: Nguyen, Linh P., Pan, Junliang, Dinh, Theresa Thanh, Hadeiba, Husein, O’Hara, Edward, Ebtikar, Ahmad, Hertweck, Arnulf, Gökmen, M. Refik, Lord, Graham M., Jenner, Richard G., Butcher, Eugene C., Habtezion, Aida
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338558/
https://ncbi.nlm.nih.gov/pubmed/25531831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3079
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