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Splicing of designer exons informs a biophysical model for exon definition

Pre-mRNA molecules in humans contain mostly short internal exons flanked by longer introns. To explain the removal of such introns, exon recognition instead of intron recognition has been proposed. We studied this exon definition using designer exons (DEs) made up of three prototype modules of our o...

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Bibliographische Detailangaben
Veröffentlicht in:RNA
Hauptverfasser: Arias, Mauricio A., Lubkin, Ashira, Chasin, Lawrence A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338349/
https://ncbi.nlm.nih.gov/pubmed/25492963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.048009.114
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