Hierarchical Clustering of Breast Cancer Methylomes Revealed Differentially Methylated and Expressed Breast Cancer Genes

Oncogenic transformation of normal cells often involves epigenetic alterations, including histone modification and DNA methylation. We conducted whole-genome bisulfite sequencing to determine the DNA methylomes of normal breast, fibroadenoma, invasive ductal carcinomas and MCF7. The emergence, disap...

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Udgivet i:PLoS One
Main Authors: Lin, I-Hsuan, Chen, Dow-Tien, Chang, Yi-Feng, Lee, Yu-Ling, Su, Chia-Hsin, Cheng, Ching, Tsai, Yi-Chien, Ng, Swee-Chuan, Chen, Hsiao-Tan, Lee, Mei-Chen, Chen, Hong-Wei, Suen, Shih-Hui, Chen, Yu-Cheng, Liu, Tze-Tze, Chang, Chuan-Hsiung, Hsu, Ming-Ta
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338251/
https://ncbi.nlm.nih.gov/pubmed/25706888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118453
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