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Local Immunosuppressive Microenvironment Enhances Migration of Melanoma Cells to Lungs in DJ-1 Knockout Mice

DJ-1 is an oncoprotein that promotes survival of cancer cells through anti-apoptosis. However, DJ-1 also plays a role in regulating IL-1β expression, and whether inflammatory microenvironment built by dysregulated DJ-1 affects cancer progression is still unclear. This study thus aimed to compare the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chien, Chia-Hung, Lee, Ming-Jen, Liou, Houng-Chi, Liou, Horng-Huei, Fu, Wen-Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338246/
https://ncbi.nlm.nih.gov/pubmed/25706411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115827
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