Perioperative Intravenous Acetaminophen Attenuates Lipid Peroxidation in Adults Undergoing Cardiopulmonary Bypass: A Randomized Clinical Trial

BACKGROUND: Cardiopulmonary bypass (CPB) lyses erythrocytes and induces lipid peroxidation, indicated by increasing plasma concentrations of free hemoglobin, F(2)-isoprostanes, and isofurans. Acetaminophen attenuates hemeprotein-mediated lipid peroxidation, reduces plasma and urine concentrations of...

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Publicat a:PLoS One
Autors principals: Billings IV, Frederic T., Petracek, Michael R., Roberts II, L. Jackson, Pretorius, Mias
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338200/
https://ncbi.nlm.nih.gov/pubmed/25705899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117625
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