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Activation of Protein Kinase by Physiological Concentrations of Cyclic AMP

When determined under the usual conditions of an excess of ligand over protein, the concentration of cyclic AMP necessary to activate pure preparations of cyclic AMP-dependent protein kinase (EC 2.7.1.37; ATP:-protein protein phosphotransferase) half-maximally is in the range of 0.2-0.3 μM when case...

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Bibliografiske detaljer
Main Authors: Beavo, J. A., Bechtel, P. J., Krebs, E. G.
Format: Artigo
Sprog:Inglês
Udgivet: 1974
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC433818/
https://ncbi.nlm.nih.gov/pubmed/4372627
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