Identification of a key residue in K(v)7.1 potassium channel essential for sensing external potassium ions

K(v)7.1 voltage-gated K(+) (K(v)) channels are present in the apical membranes of marginal cells of the stria vascularis of the inner ear, where they mediate K(+) efflux into the scala media (cochlear duct) of the cochlea. As such, they are exposed to the K(+)-rich (∼150 mM of external K(+) (K(+)(e)...

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Udgivet i:J Gen Physiol
Main Authors: Wang, Wenying, Flores, Maria Cristina Perez, Sihn, Choong-Ryoul, Kim, Hyo Jeong, Zhang, Yinuo, Doyle, Karen J., Chiamvimonvat, Nipavan, Zhang, Xiao-Dong, Yamoah, Ebenezer N.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338162/
https://ncbi.nlm.nih.gov/pubmed/25712016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411280
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