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Reversibility of the Pyrophosphoryl Transfer from ATP to GTP by Escherichia coli Stringent Factor

The stringent factor-catalyzed, ribosome-dependent synthesis of guanosine polyphosphates is found to be reversible. The reverse reaction specifically requires 5′-AMP as the pyrophosphoryl acceptor, and guanosine 5′-triphosphate-3′-diphosphate is preferentially utilized as the pyrophosphoryl donor. T...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autor Principal: Sy, Jose
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1974
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433795/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4372621/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.9.3470
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