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Novel Mechanism of Plasma Prekallikrein (PK) Activation by Vascular Smooth Muscle Cells: Evidence of the presence of PK Activator

The contribution of plasma prekallikrein (PK) to vascular remodeling is becoming increasingly recognized. Plasma PK is activated when the zymogen PK is digested to an active enzyme by activated factor XII (FXII). Here, we present our findings that vascular smooth muscle cells (VSMC) activate plasma...

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Détails bibliographiques
Publié dans:J Biol Regul Homeost Agents
Auteurs principaux: Keum, Joo-Seob, Jaffa, Miran A, Luttrell, Louis M, Jaffa, Ayad A.
Format: Artigo
Langue:Inglês
Publié: 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337887/
https://ncbi.nlm.nih.gov/pubmed/25620170
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