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Risk of false positive genetic associations in complex traits with underlying population structure: A case study

Genome-wide association (GWA) studies are widely used to investigate the genetic etiology of diseases in domestic animals. In the horse, GWA studies using 40–50,000 single nucleotide polymorphisms (SNPs) in sample sizes of 30–40 individuals, consisting of only 6–14 affected horses, have led to the d...

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Bibliografiska uppgifter
I publikationen:Vet J
Huvudupphovsmän: Finno, Carrie J., Aleman, Monica, Higgins, Robert J., Madigan, John E., Bannasch, Danika L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337777/
https://ncbi.nlm.nih.gov/pubmed/25278384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tvjl.2014.09.013
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