Quantitative system drift compensates for altered maternal inputs to the gap gene network of the scuttle fly Megaselia abdita

The segmentation gene network in insects can produce equivalent phenotypic outputs despite differences in upstream regulatory inputs between species. We investigate the mechanistic basis of this phenomenon through a systems-level analysis of the gap gene network in the scuttle fly Megaselia abdita (...

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Udgivet i:eLife
Main Authors: Wotton, Karl R, Jiménez-Guri, Eva, Crombach, Anton, Janssens, Hilde, Alcaine-Colet, Anna, Lemke, Steffen, Schmidt-Ott, Urs, Jaeger, Johannes
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2015
Fag:
Developmental Biology and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337606/
https://ncbi.nlm.nih.gov/pubmed/25560971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04785
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