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The Arf GTPase-Activating Protein Family Is Exploited by Salmonella enterica Serovar Typhimurium To Invade Nonphagocytic Host Cells

To establish intracellular infections, Salmonella bacteria trigger host cell membrane ruffling and invasion by subverting cellular Arf guanine nucleotide exchange factors (GEFs) that activate Arf1 and Arf6 GTPases by promoting GTP binding. A family of cellular Arf GTPase-activating proteins (GAPs) c...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Davidson, Anthony C., Humphreys, Daniel, Brooks, Andrew B. E., Hume, Peter J., Koronakis, Vassilis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337568/
https://ncbi.nlm.nih.gov/pubmed/25670778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02253-14
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