The Interface between Hepatitis B Virus Capsid Proteins Affects Self-Assembly, Pregenomic RNA Packaging, and Reverse Transcription

Hepatitis B virus (HBV) capsid proteins (Cps) assemble around the pregenomic RNA (pgRNA) and viral reverse transcriptase (P). pgRNA is then reverse transcribed to double-stranded DNA (dsDNA) within the capsid. The Cp assembly domain, which forms the shell of the capsid, regulates assembly kinetics a...

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Bibliographic Details
Published in:J Virol
Main Authors: Tan, Zhenning, Pionek, Karolyn, Unchwaniwala, Nuruddin, Maguire, Megan L., Loeb, Daniel D., Zlotnick, Adam
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337549/
https://ncbi.nlm.nih.gov/pubmed/25568211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03545-14
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